BIOFAC A/S launches natural Thyroid API for the treatment of hypothyroidism

20. november 2020
New API targets unmet needs of hypothyroid patients who continue suffering from symptoms despite using the standard synthetic therapy

Thyroid launch

Hypothyroidism, or underactive thyroid disease, is a state when thyroid gland does not produce enough thyroid hormones. It is a rather common disorder followed by weight gain, poor ability to tolerate cold, a feeling of tiredness, constipation, depression, fatigue and slow reflexes amongst other symptoms.

The standard hypothyroidism treatment protocol is thyroid hormone replacement with a syntethic T4 hormon - levothyroxine.  However, the evidence suggests that 5-10% of patients treated with levothyroxine exhibit persistent symptoms despite having normal thyroid-stimulating hormone (TSH) levels. (L. Chaker, A. C. Bianco, J. Jonklas, R. P. Peeters, Hypothyroidism. Lancet 2017; 390: 1550-62).

About half of all patients prefers natural thyroid powder containing T3 and T4, compared to only syntethic T4, primarily due to fewer side effects (Hoang, T. D., Olsen, C. H., Mai, V. Q., Clyde, P. W. & Shakir, M. K. M. Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study. The Journal of Clinical Endocrinology & Metabolism 98, 1982-1990 (2013).

Our natural thyroid API, extracted from porcine thyroid glands, targets this unmet demand of hypothyroidic patients. It contains hormones tetraiodothyronine, also known as thyroxine or T4, and triiodothyronine, otherwise known as liothyronine or T3 - that are naturally produced by the thyroid gland. The hormones are easily absorbed, and product can therefore be administered orally.

As it is important to have balanced levels of thyroid hormones, intake of thyroid powder should not be overdosed. To enable careful dosing of hormones Biofac Thyroid Powder is produced according to USP standards. 

BIOFAC team has been working hard towards EU GMP certification of a new production line, and we are now happy to be able to offer natural Thyroid API to our professional cooperation partners worldwide.