Hypothyroidism, or underactive thyroid disease, is a
state when thyroid gland does not produce enough thyroid hormones.
It is a rather common disorder followed by weight gain, poor
ability to tolerate cold, a feeling of
tiredness, constipation, depression, fatigue and slow
reflexes amongst other symptoms.
The standard hypothyroidism treatment protocol is thyroid
hormone replacement with a syntethic T4 hormon -
levothyroxine. However, the evidence suggests that 5-10% of
patients treated with levothyroxine exhibit persistent symptoms
despite having normal thyroid-stimulating hormone (TSH) levels.
(L. Chaker, A. C. Bianco, J. Jonklas, R. P. Peeters,
Hypothyroidism. Lancet 2017; 390: 1550-62).
About half of all patients prefers natural thyroid powder
containing T3 and T4, compared to only syntethic T4, primarily due
to fewer side effects (Hoang, T. D., Olsen, C. H., Mai, V. Q.,
Clyde, P. W. & Shakir, M. K. M. Desiccated Thyroid Extract
Compared With Levothyroxine in the Treatment of Hypothyroidism: A
Randomized, Double-Blind, Crossover Study. The Journal of Clinical
Endocrinology & Metabolism 98, 1982-1990 (2013).
Our natural thyroid API, extracted from porcine thyroid glands,
targets this unmet demand of hypothyroidic patients. It contains
hormones tetraiodothyronine, also known as thyroxine or T4, and
triiodothyronine, otherwise known as liothyronine or T3 - that are
naturally produced by the thyroid gland. The hormones
are easily absorbed, and product can therefore be administered
orally.
As it is important to have balanced levels of thyroid
hormones, intake of thyroid powder should not be overdosed. To
enable careful dosing of hormones Biofac Thyroid Powder is produced
according to USP standards.
BIOFAC team has been working hard towards EU GMP certification
of a new production line, and we are now happy to be able to offer
natural Thyroid API to our professional cooperation partners
worldwide.
