Placenta Extract (GMP)

Therapeutical Application Areas

The healing attributes of placenta have to some extent been investigated with modern scientific methods; some therapeutic properties have been confirmed, although not always explained.

From traditional folk medicine it is known that extracts from placenta contain a wide range of therapeutic agents. 

Placenta is the jewel of the cellular renewal

Traditionally, Placenta Extract is used as a drug of rejuvenation and vitalization. Many bio active- and anti-inflammatory components found in Placenta Extracts stimulate the cellular renewal and repair.
In vivo and in vitro studies suggest that Placenta Extract has a property of regenerating hepatocytes.

Yoshikawa, et al. Efficacy of Porcine Placenta Extract on wrinkle widths below the eye in climacteric women, Climacteric 2014; 17:370-376. 

Yoshikawa, et al. Effect of Porcine Placenta Extract on Collagen Production in Human Skin Fibroblasts In Vitro, Gynecol Obstet 2013. 

Liu et al. Human Placenta Extract Stimulate Liver Regeneration in Rats, Biol. Pharm, Bull, 21(1), 44-49, 1998 

Placenta Extract as a wound healing agent

In general the clinical efficacy of Placenta Extract for wound healing is established. Placenta is also shown to play a beneficial role as a topical agent in the management of chronic non-healing wounds.
The Placenta Extracts’ anti-microbial properties against a large number of pathological microorganisms, related to prevention of the secondary infections to wounds, have been demonstrated. 

Hong et al., The effect of human placenta extract in a wound healing model. Ann. Plast. Surg. 2010; 65: 96-100 

Wu et al., Wound healing effects of porcine placenta extracts on rats with thermal injury. Br. J. Dermatology 2003; 148: 236-245 

Shukla et al., A trial to determine the role of placenta extract in the treatment of chronic non-healing wounds. J. Wound Care, 2004; 13:177-179 

Other important health benefits of Placenta Extracts

The general health benefits of Placenta Extract include improvements in energy, stress response, improvement of sleep patterns, relaxation and the ability to overcome a feeling of fatigue.

It is well known that the bio-active molecules in placenta include hormones like prolactin and oxytocin – hormones that helps lactating and bonding after giving birth, as well as providing a state of happiness and enhancing the feeling of wellness and relaxation.

Oxytocin – love, happiness and lactation hormone 

Kong et al. Effect of human placenta extract on menopausal symptoms, fatigue, and risk factors for cardiovascular disease in middle-aged Korean women. Journal of The North American Menopause Society: 15:2 p. 96-30 

Key Product Features

BIOFAC Placenta Extracts grades

BIOFAC supplies following standard grades of Placenta Extracts:

  • Placenta Extract, a totally soluble in water powder for oral application.
  • Placenta Extract Liquid – developed especially for application in liquid finished forms, as syrups, ointments, and gels.
  • Low Molecular Weight Placenta Extract Powder.
  • Placenta Extracts of different origins, as bovine, sheep, horse, porcine.
  • Placenta Extract Cosmetic Grade – for application in cosmetics and cosmeceuticals.

Storage and Stability

Placenta should be stored in original and tightly closed containers or bottles at room temperature (not exceeding 25°C). Placenta Extract powder grade is a very hygroscopic product that easily absorbs humidity from the air. The recommended retest date is 2 years from date of production if stored as advised above.       

The shelf life for Porcine Placenta Extract in liquid form is 1 year from date of production.

The Placenta organ

The Placenta organThe placenta supports the baby’s growth and development in the mother’s womb; it supplies the growing fetus with biologically active components. From traditional folk medicine it is known that extracts from placenta contain a wide range of therapeutic agents. 

Placenta

Yoshikawa, et al. Efficacy of Porcine Placenta Extract on wrinkle widths below the eye in climacteric women, Climacteric 2014; 17:370-376. 

Yoshikawa, et al. Effect of Porcine Placenta Extract on Collagen Production in Human Skin Fibroblasts In Vitro, Gynecol Obstet 2013. 

Liu et al. Human Placenta Extract Stimulate Liver Regeneration in Rats, Biol. Pharm, Bull, 21(1), 44-49, 1998 

Placenta Extract

Hong et al., The effect of human placenta extract in a wound healing model. Ann. Plast. Surg. 2010; 65: 96-100 

Wu et al., Wound healing effects of porcine placenta extracts on rats with thermal injury. Br. J. Dermatology 2003; 148: 236-245 

Shukla et al., A trial to determine the role of placenta extract in the treatment of chronic non-healing wounds. J. Wound Care, 2004; 13:177-179 

Oxytocin

Oxytocin – love, happiness and lactation hormone 

Kong et al. Effect of human placenta extract on menopausal symptoms, fatigue, and risk factors for cardiovascular disease in middle-aged Korean women. Journal of The North American Menopause Society: 15:2 p. 96-30 

Regulatory Compliance

  • BIOFAC Bovine Placenta Extracts have been Halal-certified by ICC in Copenhagen – a qualified Halal-certification body, which is recognized by MUIS in Singapore and LPPOM MUI in Indonesia.
  • We manufacture BIOFAC Placenta Extracts at GMP plant under the strictest quality and environmental regulations.
    All biological raw materials utilized at the factory have been veterinary controlled and fulfil EU requirements.
  • Danish Environmental Protection Agency (Danish EPA) has made a categorization of BIOFAC as to an instruction No. 6 of 2004 on Differential Environmental Review and assessed that BIOFAC is placed in Category 1 (the best category) because of the high level of systematism and high level of regulatory compliance.

  • Danish Working Environment Authority has given BIOFAC a green Smiley, indicating that BIOFAC has no issues with the Working Environment Authority, providing a high level of health and safety.

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